1.
Mansoura Medical Bulletin. 1978; 6 (1): 35-46
in English
| IMEMR
| ID: emr-136190
ABSTRACT
The aim of the present work was a study of the acute toxicity, the anti-inflammatory activity as the analgesic potency of salicylates, oxyphenbutazone, hydrocortisone and propranolol The L.D[50] was found to be 300 mg/kg., 460 mg/kg., 750 mg/kg. and 36 mg/kg respectively. All tested drugs induced a significant anti-inflammatory activity sod. Salicylate was the most potent, while propranolol was the least effective one. Sod. salicylate, hydrocortisone and oxyphenbutazone exerted a significant analgesic activity following the hot plate method, but by using the tail compression test only sod. salicylate exerted analgesic activity